I'd also like to see the output of what Rick asked for but I'd recommend starting your servers with --skip-innodb to completely skip Innodb (if you don't have Innodb tables).
I also think that its too early to predict the buffer size since we dont know the size of indexes yet.
Please use the following to find the no. of tables in the DB for us. And, also tell us the values of caches (SHOW GLOBAL VARIABLES LIKE %cache%) and buffers (SHOW GLOBAL VARIABLES LIKE %buffer%)
mysql> use information_schema;
mysql> SELECT COUNT(*) FROM TABLES;
You'll also have to monitor your status variables to come up with good numbers since we cannot predict the kind of load you are expecting.
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