RAM settings need to be tailored to loads & resources. What is the MySQL version? What is innodb_buffer_pool_size? How much RAM does the machine have, how much is used by other processes?
Then please ...
(i) post the result of ...
select engine,data,indexes,total
from (
select
ifnull(engine,'TOTALS') as engine,
concat(data,' GB') as data,
concat(indexes,' GB') as indexes,
concat(tot,' GB') as total,
if(engine is null,-1,tot) as ord
from (
select
engine,
round( sum(data_length)/1024/1024/1024, 2 ) as data,
round( sum(index_length)/1024/1024/1024, 2 ) as indexes,
round( sum(data_length+index_length)/1024/1024/1024, 2 ) as tot
from information_schema.tables
where engine is not null and engine not in('information_schema','performance_schema')
group by engine with rollup
) sums
) list
order by list.ord desc;
(ii) post the results of running the following queries in the mysql client program ...
show variables;
show global status;
-- if mysql 5.7 or later ...
select * from sys.memory_global_total;
select
substring_index(event_name,'/',2) as code_area,
sys.format_bytes( sum(current_alloc) ) as current_alloc
from sys.x$memory_global_by_current_bytes
group by substring_index(event_name,'/',2)
order by sum(current_alloc) desc;
select
concat(format(a.num * 100.0 / b.num,2),"%") bufferpoolfullpct
from
(select variable_value num from performance_schema.global_status
where variable_name = 'innodb_buffer_pool_pages_data') a,
(select variable_value num from performance_schema.global_status
where variable_name = 'innodb_buffer_pool_pages_total') b;
[/code]
-- and look for runaway mem use in the results of ...
select *
from performance_schema.memory_summary_global_by_event_name
where event_name like 'memory/performance_schema/%';
(iii) post the result of running from the terminal prompt ...
free -m